Activated Factor VIII

《英文msh詞典》Activated Factor VIII
[入口詞] Activated Factor VIII
[主題詞] Factor VIIIa
[中文釋義] 活化的因子Ⅷ
[英文釋義] Activated form of factor VIII. The B-domain of factor VIII is proteolytically cleaved by thrombin to form factor VIIIa. Factor VIIIa exists as a non-covalent dimer in a metal-linked (probably calcium) complex and functions as a cofactor in the enzymatic activation of factor X by factor IXa. Factor VIIIa is similiar in structure and generation to factor Va.